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Corona Vaccine News: Covaxin and Covishield approv in India, but Pfizer and Moderna vaccines are better

Durgesh Nandan Jha, New Delhi
Is a dose of the vaccine developed against the Kovid-19 pandemic enough to protect against corona virus infection? If not, is it okay to wait for a more effective vaccine by taking a dose of the current vaccine? That is, after giving a Corona vaccine for the first time, would it be appropriate to take a more effective vaccine a second time in the future? This is the first time the answer to these questions has been revealed. The United States Food and Drug Administration (FDA), the regulatory body of the United States, said in a very clear answer to this question that no.

The United States Regulatory Body Answered Important Questions
He said that Pfizer-BioNTech and Moderna Vaccine are establishing themselves in the country. Both vaccines have produced approximately 95% immunity against coronavirus infection in adults. The US FDA stated: “We are aware of the discussions and news about decreasing vaccine doses. There are discussions between two doses of vaccine to increase the gap, change the dose (half or full dose). or administer different doses of vaccine. ” So that more and more people can be protected against Kovid-19 Mahama. These are absolutely logical questions that must be considered and the answers must be found through clinical trials. Or it would not be correct to change the time interval between two doses etc. as there is no solid basis for the existing evidence to do so.

Expert advice – do not mix vaccine
An interval of 21 days has been fixed for the two doses of the Pfizer-BioNotech vaccine while 28 days for the Moderna. Public health experts say that the same rules will be adopted in India on the Kovid vaccine. Vaccination can start here in the next 9 days. Dr. NK Mehra, a scientist at the Indian Council of Aeronautical Research (ICMR) and the former All India Institute of Medical Sciences (AIIMS), insisted, “You cannot mix the vaccine and the second of the vaccine to produce immunity against the coronavirus The dose is very important. “He said that the effect of mixing two different vaccines may not have been researched, so it is not advisable to give one dose of a vaccine and another dose of another vaccine.

Will a second vaccine be installed after applying conviction or covicshield?
The country’s own Covaxin in India and Covishield developed by the University of Oxford and AstraZeneca have been approved for limited emergency use. India uses the killed coronavirus to boost the immune system in the production of colicin antibodies developed by biotechnology and ICMR. At the same time, the chimpanzee Kovishield destroys the coronavirus spike protein genes using a scaled-down version of adenovirus. The coronavirus uses only the genes for this spike protein to enter the human cell. The adenovirus is modified so that it does not form its second form but instead identifies the genes for the peak protein of the cells. This causes the immune system to react and develop antibodies against COVID. Two doses of both vaccines, Kovaxin and Kovishield, will be administered.

How likely are Pfizer and Moderna to be vaccinated in India?
The Pfizer and Moderna vaccines have been developed on the messenger RNA platform and are therefore different from Covaxin and Coveshield. mRNA is the genetic material that our cells use to make proteins. “The Pfizer and Moderna vaccines are most effective but should be stored at temperatures of -70 ° C and -20 ° C respectively,” says Dr. Sunila Garg, public health expert and designated master trainer for the vaccination campaign in Delhi . . She added: “The vaccines in India do not have enough storage capacity at such low temperatures. It is also a challenge to manage them. Therefore, I do not think that the Pfizer and Moderna vaccines could be available in India.

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