Indiana on Friday became the first state in the US to approve abortion restrictions.

The ban takes effect September 15 but includes some exceptions.

Abortions would be permitted in cases of rape and incest, before 10-weeks post-fertilisation; to protect the life and health of the mother.

And if a fetus is diagnosed with a lethal anomaly.

Victims of rape and incest would not be required to sign a notarised affidavit attesting to an attack.

Under the bill, abortions can be performed only in hospitals or outpatient centres owned by hospitals.

All abortion clinics would lose their licences.

A doctor who performs an illegal abortion or fails to file required reports must also lose their medical licence.

Indiana was among the earliest Republican-run state legislatures to debate tighter abortion laws.

On average, there are 463,634 victims (age 12 or older) of rape and sexual assault each year in the US.